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Coronavirus outbreak: An inexplicable link between people with vitamin D deficiency who are infected with COVID-19



There may be a link between people suffering from vitamin D deficiency and infection with COVID-19 and the mortality rate.

This study was carried out by researchers from Northwestern University and its results have been published in the diary medRxiv.

Vadim Backman, the lead author of this study, and Walter Dill Scott, professor of biomedical engineering at the McCormick School of Engineering in the Northwest, found differences in mortality rates from country to country, and there were some theories that related to the quality of the health care system Age related to test rates or different stresses The virus could be responsible. However, he was not convinced.

    Coronavirus outbreak: An inexplicable link between people with vitamin D deficiency who are infected with COVID-19

There is a link between people who have vitamin D deficiency, are infected with COVID-19 and have higher mortality rates.

“None of these factors seem to play a significant role,” said Backman in a statement. “The healthcare system in northern Italy is one of the best in the world. There are also differences in mortality when you look at the same age group. And although the test restrictions are actually different, the differences in mortality still exist when we look at countries or population groups that have similar test rates. Instead, we saw a significant correlation with vitamin D deficiency. “

The research team examined patients from countries with high COVID-19 mortality rates, such as Italy, Spain and the UK, and found that infected patients had lower vitamin D levels compared to patients in countries that were not as badly affected. They also found a strong correlation between vitamin D levels and cytokine storm – a hyperinflammatory condition caused by an overactive immune system.

“The cytokine storm can severely damage the lungs and lead to acute respiratory distress syndrome and death in patients,” said Ali Daneshkhah, a postdoc and lead author of the paper. in a statement. “This appears to kill the majority of COVID-19 patients, not the destruction of the lungs by the virus itself. It is the complication of the misguided fire of the immune system. “

Immunity to the virus

We have two types of immune systems – an acquired immune system and the innate immune system.

Acquired immunity or adaptive immunity creates an immunological memory after an initial response to a particular pathogen and offer permanent protection against the pathogen.

The innate immune system is an older evolutionary defense strategy and comes into play within hours after an antigen appears in the body. These mechanisms include physical barriers such as skin, chemicals in the blood, and immune system cells that attack foreign cells in the body The biology project from the University of Arizona.

Backman also explained why child mortality rates for COVID-19 are lower. He said: “Children do not have a fully developed acquired immune system, which is the second line of defense of the immune system and is more likely to overreact.”

“Children rely mostly on their innate immune systems,” Backman added in the statement. “This could explain why their mortality rate is lower.”

Why is vitamin D so important?

According to the statementVitamin D strengthens our immune system and prevents our immune system from becoming overactive. Healthy vitamin D levels could protect patients from serious complications, including death, from COVID-19.

Taking supplements is a great way to make sure you get your daily dose of vitamin D. Another way to get vitamin D is to expose yourself to natural sunlight.

However, NHS states Taking too many vitamin D supplements for a long period of time can cause too much calcium to accumulate in the body. This can weaken the bones and damage the kidneys and heart.

Backman said: “However, it is clear that vitamin D deficiency is harmful and can be easily remedied with a suitable supplement. This could be another key to protecting vulnerable groups, such as African-American and elderly, who have vitamin D deficiency. “

Updated on: May 15, 2020 1:29:23 PM IST

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